Medline ® Abstract for Reference 28
of 'Overview of the treatment of acute lymphoblastic leukemia in children and adolescents'
Imatinib mesylate in combination with chemotherapy in four children with de novo and advanced stage Philadelphia chromosome-positive acute lymphoblastic leukemia.
Fuster JL, Bermúdez M, Galera A, Llinares ME, Calle D, Ortuño FJ
The role of imatinib in childhood Philadelphia chromosome-positive (Ph(+)) acute lymphoblastic leukemia (ALL) has not been established. We treated four children with imatinib in combination with conventional chemotherapy (CT) before stem cell transplantation (SCT). Response evaluation consisted of fluorocytometric analysis of minimal residual disease (MRD) and standard qualitative RT-PCR follow-up.
Hospital Universitario Virgen de la Arrixaca, Murcia, Spain. firstname.lastname@example.org