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Medline ® Abstract for Reference 135

of 'Overview of the management of epilepsy in adults'

135
TI
Gabapentin in late-onset poststroke seizures.
AU
Alvarez-Sabín J, Montaner J, PadróL, Molina CA, Rovira R, Codina A, Quintana M
SO
Neurology. 2002;59(12):1991.
 
Stroke is a frequent cause of epileptic seizures (ES) in adults. The authors evaluated the long-term efficacy and tolerability of gabapentin (900 to 1,800 mg/day) in 71 patients with a first poststroke late ES during a mean follow-up time of 30 months. ES recurred in 18.3% of the patients and side effects were noted in 27 cases (38%), but only two (2.8%) required discontinuation or early withdrawal. Gabapentin monotherapy was useful and safe for late poststroke ES.
AD
Cerebrovascular Unit, Department of Neurology, Hospital Vall d'Hebron, Barcelona, Spain. alsa@hg.vhebron.es
PMID