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Overview of prevention of opportunistic infections in HIV-infected patients

Authors
John G Bartlett, MD
Paul E Sax, MD
Section Editor
Martin S Hirsch, MD
Deputy Editor
Jennifer Mitty, MD, MPH

INTRODUCTION

Untreated HIV infection and HIV-related immunosuppression significantly increase the risk of acquiring opportunistic infections due to bacteria, viruses, fungi, and protozoa. These opportunistic infections were a major source of morbidity and mortality in HIV-infected patients prior to the development of effective antiretroviral therapy (ART) and still occur today, mostly in patients who are not receiving ART. Substantial advances in the prevention of opportunistic infections have been achieved. These strategies involve the use of antimicrobials, immunizations, and public health measures.

An overview of these different strategies will be reviewed here. The clinical manifestations, diagnosis, and treatment of specific opportunistic infections, as well as the use of secondary prophylaxis, are discussed elsewhere.

(See "Treatment and prevention of Pneumocystis infection in HIV-infected patients".)

(See "Toxoplasmosis in HIV-infected patients".)

(See "Mycobacterium avium complex (MAC) infections in HIV-infected patients".)

                     

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Literature review current through: Nov 2016. | This topic last updated: Tue Nov 17 00:00:00 GMT+00:00 2015.
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References
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