Medline ® Abstract for Reference 214
of 'Overview of neurologic complications of non-platinum cancer chemotherapy'
Parkinsonism induced by high-dose cytosine arabinoside.
Luque FA, Selhorst JB, Petruska P
Mov Disord. 1987;2(3):219.
We report a severe parkinsonian condition following high dose, parenteral cytosine arabinoside (Cytosar) that persisted for 8 weeks. The drug was used in a patient with acute myelogenous leukemia that was refractory to all other treatment. The syndrome was partially responsive to antiparkinsonian drugs and fortunately remitted completely within 12 weeks.
Department of Neurology, Saint Louis University School of Medicine, Missouri 63110.