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Overview of immunosuppressive and conventional (non-biologic) disease-modifying drugs in the rheumatic diseases

Philip Seo, MD
Section Editor
Daniel E Furst, MD
Deputy Editor
Paul L Romain, MD


Immunosuppressive drugs other than glucocorticoids are used in the treatment of various rheumatologic conditions to achieve one or more of the following goals:

To induce or maintain a remission

To reduce the frequency of flare or relapse

To allow tapering of glucocorticoids while maintaining disease control

This topic review will provide an overview of the use of immunosuppressive drugs in various rheumatic diseases, including the conventional (non-biologic) disease-modifying antirheumatic drugs (DMARDs), sometimes referred to as traditional DMARDs. Detailed discussions concerning the use of these drugs in specific rheumatic disorders are presented in the appropriate topic reviews covering the treatment of each condition.


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Literature review current through: Sep 2016. | This topic last updated: May 19, 2016.
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