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Overview of endometrial carcinoma

Steven C Plaxe, MD
Arno J Mundt, MD
Section Editors
Barbara Goff, MD
Don S Dizon, MD, FACP
Deputy Editors
Sadhna R Vora, MD
Sandy J Falk, MD, FACOG


Cancer of the endometrium (lining of the uterus) is the most common gynecologic malignancy in developed countries and the second most common in developing countries (cervical cancer is more common). Endometrioid carcinoma is the common site and histologic subtype of endometrial carcinoma and of uterine cancer overall. Endometrioid tumors tend to have a favorable prognosis and typically present at an early stage with abnormal uterine bleeding. Other histologic types of endometrial carcinoma (eg, serous, clear cell) as well as other types of uterine cancer are associated with a poor prognosis.

An overview of endometrial carcinoma will be presented here. Related topics are discussed in detail separately, including:

Histopathology and pathogenesis (see "Endometrial carcinoma: Histopathology and pathogenesis")

Epidemiology and risk factors (see "Endometrial carcinoma: Epidemiology and risk factors")

Clinical features, diagnosis, and screening for high-risk women (see "Endometrial carcinoma: Clinical features and diagnosis")


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Literature review current through: Sep 2016. | This topic last updated: Jun 6, 2016.
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