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Medline ® Abstract for Reference 17

of 'Overview of cancer pain syndromes'

Recurrence in skeletal muscle from squamous cell carcinoma of the uterine cervix: a case report and review of the literature.
Ferrandina G, Salutari V, Testa A, Zannoni GF, Petrillo M, Scambia G
BMC Cancer. 2006;6:169. Epub 2006 Jun 27.
BACKGROUND: The occurrence of skeletal muscle metastases is a very rare event. Only two cases of late skeletal muscle recurrence from cervical cancer have been documented until now.
CASE PRESENTATION: A 38-year old patient, submitted to radical hysterectomy and pelvic lymphadenectomy for a squamous FIGO stage IB1 cervical carcinoma, presented after 76 months with a palpable, and painless swelling on the left hemithorax. MRI showed a nodule located in the context of the intercostal muscles. Pathology revealed the presence of metastasis of squamous cell carcinoma of similar morphology as the primary. On the basis of FDG-PET findings, which excluded other sites of disease, surgical excision of the lesion was performed. The patient was triaged to chemotherapy plus external radiotherapy.
CONCLUSION: A case of skeletal muscle recurrence from cervical cancer after a very long interval from primary diagnosis is reported. Muscular pain or weakness, or just a palpable mass in a patient with a history of cancer has always to raise the suspicion of muscle metastasis.
Gynecologic Oncology Unit, Catholic University, L.go Gemelli 8, 00168, Rome, Italy. gabriella.ferrandina@libero.it