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Opioid intoxication in children and adolescents

Shan Yin, MD, MPH
Section Editor
Michele M Burns, MD, MPH
Deputy Editor
James F Wiley, II, MD, MPH


The epidemiology, pharmacology, clinical manifestations, and management of opioid toxicity in children and adolescents are reviewed here.

Opioid withdrawal in the pediatric patient and opioid use disorder, intoxication, withdrawal, and treatment in adults are discussed separately. (See "Neonatal abstinence syndrome" and "Opioid withdrawal in adolescents" and "Opioid use disorder: Epidemiology, pharmacology, clinical manifestations, course, screening, assessment, and diagnosis" and "Pharmacotherapy for opioid use disorder" and "Acute opioid intoxication in adults".)


Several terms are used to describe opioid substances:

Opioid refers to natural and synthetic substances with morphine-like activity.

Opiate describes a subclass of opioids consisting of alkaloid compounds extracted from opium, including morphine, heroin, codeine, and semisynthetic derivatives of the poppy plant.

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Literature review current through: Nov 2017. | This topic last updated: Aug 24, 2017.
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