Medline ® Abstract for Reference 25
of 'Nonarteritic ischemic optic neuropathy: Prognosis and treatment'
The effect of aspirin on the visual outcome of nonarteritic anterior ischemic optic neuropathy.
Botelho PJ, Johnson LN, Arnold AC
Am J Ophthalmol. 1996;121(4):450.
PURPOSE: To examine the effect of aspirin use on the visual outcome of nonarteritic anterior ischemic optic neuropathy.
METHODS: This retrospective case-controlled study included 23 patients who used aspirin regularly before and during the course of nonarteritic anterior ischemic optic neuropathy and 55 control patients with nonarteritic anterior ischemic optic neuropathy. Snellen visual acuity in logMAR and mean deviation on automated perimetry were compiled from the initial and final follow-up examinations.
RESULTS: The comparisons of patients who took aspirin with control patients disclosed that neither initial logMAR (P = .36) nor the follow-up logMAR (P = .95) data differed significantly. There was no significant difference between the groups for the initial (P = .60) and the follow-up mean deviation (P = .41).
CONCLUSIONS: Aspirin use does not improve the visual outcome of patients with nonarteritic anterior ischemic optic neuropathy. Additional studies are needed to further elucidate this issue.
Mason Institute of Ophthalmology, University of Missouri-Columbia, Missouri 65212, USA.