Medline ® Abstract for Reference 32
of 'Nocturnal leg cramps'
32
TI
Naftidrofuryl treatment for rest cramp.
AU
Young JB, Connolly MJ
SO
Postgrad Med J. 1993;69(814):624.
A double-blind placebo-controlled study was carried out in 14 subjects to investigate the effect of naftidrofuryl in the treatment of rest cramp. Naftidrofuryl caused a significant reduction in cramp frequency (median naftidrofuryl = 5; median placebo = 17; P<0.004) and a significant 34% increase in cramp free days (median naftidrofuryl = 22; median placebo = 14; P<0.004). Naftidrofuryl is an effective alternative to quinine in the treatment of this painful condition.
AD
St Luke's Hospital, Bradford, UK.
PMID