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Medline ® Abstracts for References 7,8

of 'Nocturnal enuresis in children: Management'

7
TI
Nocturnal enuresis.
AU
Kiddoo D
SO
BMJ Clin Evid. 2007;2007
 
INTRODUCTION: Nocturnal enuresis affects 15-20% of 5-year-old children, 5% of 10 year-old-children and 1-2% of people aged 15 years and over. Without treatment, 15% of affected children will become dry each year. Nocturnal enuresis is not diagnosed in children younger than 5 years, and treatment may be inappropriate for children younger than 7 years.
METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of interventions for relief of symptoms? We searched: Medline, Embase, The Cochrane Library and other important databases up to March 2007 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS: We found 14 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupuncture, anticholinergics (oxybutynin, tolterodine, hyoscyamine), desmopression, dry bed training, enuresis alarm, hypnotherapy, standard home alarm clock, tricyclics (imipramine, desipramine).
AD
University of Alberta, Alberta, Canada.
PMID
8
TI
Nocturnal enuresis.
AU
Schmitt BD
SO
Pediatr Rev. 1997;18(6):183.
 
The answer to nocturnal enuresis is nocturnal self-awakening. Enuresis alarms teach this skill and, therefore, have the highest cure rate and the lowest relapse rate of any intervention. An alarm costs the same as a 2-week supply of desmopressin. Alarms can be used anytime from age 5 onward if the child elects to use one. If an alarm alone is not successful, combining it with medication increases the cure rate. The ability to teach a family how to use an enuresis alarm is an important part of pediatric office practice.
AD
University of Colorado School of Medicine, Denver, USA.
PMID