Nitrofurantoin-induced pulmonary injury
- Justus de Zeeuw, MD
Justus de Zeeuw, MD
- Wuppertal, Germany
- Jochen Schumacher, MD
Jochen Schumacher, MD
- Senior Resident
- Alfried Krupp Krankenhaus Essen, Germany
- Adrian G Gillissen, MD, PhD, MSc
Adrian G Gillissen, MD, PhD, MSc
- Professor of Medicine
- General Hospital, Kassel, Kassel School of Medicine, Germany
Nitrofurantoin is an antibacterial agent frequently used in the management of urinary tract infections (UTIs). This antimicrobial drug is generally used in the following clinical settings:
●The short-term prophylaxis of infections acquired by invasive urologic diagnostic procedures and operations
●The long-term prevention of recurrent UTIs
●The treatment of acute or recurrent cystitis
The most common adverse reactions to nitrofurantoin (apart from turning the urine color a harmless brown) are nausea (8 percent), headache (6 percent), and flatulence (1.5 percent). Among the rare adverse reactions (<1 percent), pulmonary injury is the most severe .
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