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Neuromuscular manifestations of systemic sclerosis (scleroderma)

Authors
Monica L Piecyk, MD
Peter H Schur, MD
Section Editor
John S Axford, DSc, MD, FRCP, FRCPCH
Deputy Editor
Monica Ramirez Curtis, MD, MPH

INTRODUCTION

The literature addressing neurologic involvement in systemic sclerosis (SSc; scleroderma) principally consists of case series and case reports. It includes the following categories, listed in approximate order of frequency:

Cranial, entrapment, peripheral, cutaneous, autonomic neuropathies

Myopathy

Central nervous system involvement, including headache, seizures, stroke, vascular disease, radiculopathy, and myelopathy

In general, however, central nervous system (CNS) involvement due to SSc is rare, but complications of other organ damage may have neurologic manifestations. Examples include renal failure, uncontrolled hypertension, and heart or respiratory failure.

                                  

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Literature review current through: Nov 2016. | This topic last updated: Fri Aug 26 00:00:00 GMT 2016.
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