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Medline ® Abstract for Reference 55

of 'Neurogenic pulmonary edema'

Medulla oblongata edema associated with neurogenic pulmonary edema. Case report.
Brown RH Jr, Beyerl BD, Iseke R, Lavyne MH
J Neurosurg. 1986 Mar;64(3):494-500.
Neurogenic pulmonary edema (NPE) occurs in association with central nervous system disease without underlying cardiopulmonary problems. It is characterized by profound pulmonary vascular congestion and a fulminant clinical course. Although several reports document a role for experimental brain-stem lesions in the production of NPE, there have been only two studies in man correlating specific brain-stem lesions with NPE. The authors report a case of NPE occurring in a patient with von Hippel-Lindau disease and a dorsal medullary syrinx with postoperative dorsal medullary edema. The anatomical location of this patient's lesion is reviewed in the context of alternative theories of the pathogenesis of NPE.