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Neonatal herpes simplex virus infection: Management and prevention

Gail J Demmler-Harrison, MD
Section Editors
Sheldon L Kaplan, MD
Leonard E Weisman, MD
Deputy Editor
Carrie Armsby, MD, MPH


Neonatal infection with herpes simplex virus (HSV) occurs in 1 out of every 3200 to 10,000 live births, causes serious morbidity and mortality, and leaves many survivors with permanent sequelae [1-4]. Despite this seemingly low prevalence, neonatal HSV accounts for 0.2 percent of neonatal hospitalizations and 0.6 percent of in-hospital neonatal deaths in the United States, and is associated with substantial healthcare resource utilization [5-8].

The management and prevention of neonatal HSV infection will be reviewed here. The clinical features and diagnosis of neonatal HSV infection and non-neonatal herpes simplex virus infection are discussed separately:

(See "Neonatal herpes simplex virus infection: Clinical features and diagnosis".)

(See "Genital herpes simplex virus infection and pregnancy".)

(See "Herpetic gingivostomatitis in young children".)

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Literature review current through: Nov 2017. | This topic last updated: Aug 29, 2017.
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