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Neonatal and infantile erythroderma

Moise L Levy, MD
Section Editor
Jonathan A Dyer, MD
Deputy Editor
Rosamaria Corona, MD, DSc


Erythroderma is a diffuse and persistent erythema of the skin involving at least 90 percent of the body surface [1]. Although relatively uncommon in pediatric patients, erythroderma may be the clinical presentation of a wide range of acquired and inherited diseases, including infections, inflammatory skin diseases, ichthyoses, and congenital immunodeficiencies.

This topic will review the causes of erythroderma in neonates and infants and the approach to the diagnosis and management. Erythroderma in adults is discussed separately. (See "Erythroderma in adults".)


Neonatal and infantile erythrodermas are associated with a wide range of cutaneous and systemic disorders, including [1-3]:

Infectious diseases (eg, staphylococcal scalded skin syndrome, congenital cutaneous candidiasis, syphilis)

Inflammatory diseases (eg, atopic dermatitis, seborrheic dermatitis, psoriasis)


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Literature review current through: Sep 2016. | This topic last updated: Sep 17, 2014.
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