Necrotizing myositis and septic shock caused by Haemophilus influenzae type f in a previously healthy man diagnosed with an IgG3 and a mannose-binding lectin deficiency

Scand J Infect Dis. 2011 Dec;43(11-12):972-6. doi: 10.3109/00365548.2011.589079. Epub 2011 Jul 5.

Abstract

An increased incidence of infections by Haemophilus influenzae type f (Hif) has recently been suggested, but such infections have mainly been regarded as opportunistic. We present here a dramatic case of Hif necrotizing myositis and septic shock. A subsequently diagnosed IgG3 and mannose-binding lectin deficiency possibly contributed to the severe outcome.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Haemophilus Infections / diagnosis*
  • Haemophilus Infections / microbiology
  • Haemophilus Infections / pathology
  • Haemophilus influenzae / classification
  • Haemophilus influenzae / isolation & purification*
  • Histocytochemistry
  • Humans
  • Immunologic Deficiency Syndromes / complications*
  • Male
  • Mannose-Binding Lectin / deficiency*
  • Microscopy
  • Muscles / pathology
  • Myositis / complications*
  • Myositis / diagnosis*
  • Myositis / microbiology
  • Myositis / pathology
  • Necrosis / pathology
  • Shock, Septic / diagnosis*
  • Shock, Septic / microbiology
  • Shock, Septic / pathology

Substances

  • Mannose-Binding Lectin