Medline ® Abstract for Reference 26
of 'Mycobacterium bovis'
26
TI
Identification of a familial cluster of pulmonary Mycobacterium bovis disease.
AU
LoBue PA, Betancourt W, Cowan L, Seli L, Peter C, Moser KS
SO
Int J Tuberc Lung Dis. 2004;8(9):1142.
SETTING:
Local public health department.
DESIGN:
Retrospective review of a cluster of three pulmonary Mycobacterium bovis cases occurring in a family, with genotyping of M. bovis strains isolated from the family members.
RESULTS:
The genotypes of the M. bovis isolates were identical, as determined by three different methods: IS6110 restriction fragment length polymorphism, spoligoytping and mycobacterial interspersed repetitive units-variable number tandem repeat analyses.
CONCLUSION:
The identification of three acid-fast bacilli (AFB) smear-positive pulmonary M. bovis cases, presenting in a single family and caused by an identical strain, suggests that person-to-person transmission of this organism may have occurred, although infection of one or more family members through ingestion of a contaminated dairy product could not be excluded.
AD
Field Services and Evaluation Branch, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia 30333, USA. pgl5@cdc.gov
PMID