Medline ® Abstract for Reference 31
of 'Molecular genetics of colorectal cancer'
The GTPase superfamily: conserved structure and molecular mechanism.
Bourne HR, Sanders DA, McCormick F
GTPases are conserved molecular switches, built according to a common structural design. Rapidly accruing knowledge of individual GTPases--crystal structures, biochemical properties, or results of molecular genetic experiments--support and generate hypotheses relating structure to function in other members of the diverse family of GTPases.
Department of Pharmacology, University of California, San Francisco 94143-0450.