Medline ® Abstract for Reference 29
of 'Microcephaly in infants and children: Etiology and evaluation'
Fetal brain disruption sequence: a milder variant.
Bönnemann CG, Meinecke P
J Med Genet. 1990;27(4):273.
We report on a female infant with severe microcephaly, scalp rugae, overlapping sutures, and telancephalic damage with relatively satisfactory early motor development. This case represents a milder form of the 'fetal brain disruption sequence', which is thought to be the result of an exogenous insult to the developing brain during the second half of gestation.
Altonaer Kinderkrankenhaus, Hamburg, Federal Republic of Germany.