Microbiology and pathogenesis of Streptococcus pneumoniae
- Elaine I Tuomanen, MD
Elaine I Tuomanen, MD
- Chair, Infectious Diseases
- St Jude Children's Research Hospital
- Section Editors
- Daniel J Sexton, MD
Daniel J Sexton, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Bacterial Infections
- Professor of Medicine
- Duke University Medical Center
- Sheldon L Kaplan, MD
Sheldon L Kaplan, MD
- Editor-in-Chief — Pediatrics
- Section Editor — Pediatric Infectious Diseases
- Professor and Vice Chairman for Clinical Affairs
- Baylor College of Medicine
Streptococcus pneumoniae occupies an important position in the history of microbiology:
●The organism was first identified in 1881.
●Its role in causing lobar pneumonia was appreciated by the late 1880s.
●The central role of antibody in host defense against extracellular organisms was first described for the pneumococcus.
●The first recognition that antibody directed to the capsular polysaccharide of a bacteria could be protective was shown for the pneumococcus; this observation forms the basis for many current bacterial vaccines.
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