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Metastatic breast cancer: Local treatment

Michael S Sabel, MD
Section Editor
Daniel F Hayes, MD
Deputy Editor
Sadhna R Vora, MD


A small but important subset of patients with metastatic breast cancer have limited systemic tumor burden and biologically indolent disease. They represent less than five percent of patients with newly diagnosed metastatic breast cancer [1-3]. However, for such patients, an intensified multidisciplinary approach combining systemic therapies with surgery, radiation, and regional chemotherapy may not only prevent local complications, but prolong survival.

Local treatment of breast cancer metastases is reviewed here. Systemic therapy and general principles of management of metastatic breast cancer, including treatment of the breast primary in the metastatic setting, treatment of brain and bone metastases, and management of locoregionally recurrent breast cancer are discussed separately.

(See "Systemic treatment for metastatic breast cancer: General principles".)

(See "Management of brain metastases in breast cancer".)

(See "Overview of the use of osteoclast inhibitors in early breast cancer".)


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Literature review current through: Sep 2016. | This topic last updated: Dec 10, 2015.
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