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Measles, mumps, and rubella immunization in adults

Author
Patricia L Hibberd, MD, PhD
Section Editor
Martin S Hirsch, MD
Deputy Editor
Elinor L Baron, MD, DTMH

INTRODUCTION

The combination measles, mumps, and rubella (MMR) vaccine includes live virus vaccines against measles, mumps, and rubella; it is an important tool for preventing serious illness due to these infections [1].

Issues related to the use of combination MMR vaccine in adults will be discussed here; use of MMR immunization in infants, children, and adolescents is discussed separately. (See "Measles, mumps, and rubella immunization in infants, children, and adolescents" and "Approach to immunizations in healthy adults".)

Issues related to the epidemiology, clinical manifestations, diagnosis, and management of measles, mumps, and rubella are discussed separately. (See "Measles: Clinical manifestations, diagnosis, treatment, and prevention" and "Mumps" and "Rubella".)

MEASLES, MUMPS, AND RUBELLA INFECTIONS

The measles virus causes an acute infection characterized by fever, cough, coryza, conjunctivitis, rash (picture 1A-B), and enanthem (picture 2) that may be followed by severe complications including encephalitis. Adults with measles are at increased risk of mortality compared with older children, and measles in pregnancy is associated with premature labor and spontaneous abortion [2]. (See "Measles: Clinical manifestations, diagnosis, treatment, and prevention".)

The mumps virus causes an acute infection characterized by parotid swelling (picture 3). Mumps infection usually is self-limited but may be associated with complications including orchitis and oophoritis, aseptic meningitis, and encephalitis. The most serious complications of mumps arise more frequently in adults than in children, including neurologic complications. (See "Mumps", section on 'Clinical features'.)

                             

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Literature review current through: Nov 2016. | This topic last updated: Tue Nov 29 00:00:00 GMT+00:00 2016.
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