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Mastocytosis (cutaneous and systemic): Evaluation and diagnosis in children

Mariana C Castells, MD, PhD
Cem Akin, MD, PhD
Section Editor
Sarbjit Saini, MD
Deputy Editor
Anna M Feldweg, MD


Mastocytosis describes a group of disorders in which there is pathologic accumulation of mast cells in tissues. These diseases can be limited to the skin (cutaneous mastocytosis [CM]) or involve extracutaneous tissues (systemic mastocytosis [SM]).

The evaluation and diagnosis of the different forms of CM and SM in children are reviewed here. The evaluation and diagnosis in adults, the clinical manifestations of mastocytosis, the treatment of mastocytosis, and the biology of mast cells are discussed separately:

(See "Mastocytosis (cutaneous and systemic): Evaluation and diagnosis in adults".)

(See "Mastocytosis (cutaneous and systemic): Epidemiology, pathogenesis, and clinical manifestations".)

(See "Treatment and prognosis of cutaneous mastocytosis".)

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Literature review current through: Nov 2017. | This topic last updated: Jun 15, 2017.
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