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Management of the infant with ambiguous genitalia

Christopher P Houk, MD
Lynne L Levitsky, MD
Section Editors
Laurence S Baskin, MD, FAAP
Mitchell E Geffner, MD
Deputy Editor
Alison G Hoppin, MD


Individuals with a congenital discrepancy between external genitalia and gonadal and chromosomal sex are classified as having a disorder of sex development (DSD) [1]. Many of these individuals present as newborns with an atypical genital appearance often termed "ambiguous genitalia". The birth of an infant with ambiguous genitalia presents a unique set of challenging management issues.

Psychosexual development is influenced by multiple factors including:

Genes involved in sexual development

Gender differences in brain structure

Prenatal androgen exposure


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Literature review current through: Nov 2016. | This topic last updated: Tue Apr 12 00:00:00 GMT 2016.
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