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Management of locally advanced cervical cancer

J Michael Straughn, Jr, MD
Catheryn Yashar, MD
Section Editors
Barbara Goff, MD
Arno J Mundt, MD
Don S Dizon, MD, FACP
Deputy Editors
Sadhna R Vora, MD
Sandy J Falk, MD, FACOG


Women with locally advanced cervical cancer (stage IB2 to IVA) have a higher rate of recurrence and worse survival than those with early-stage disease (stage IA to IB1). After surgery alone, the rate of relapse is at least 30 percent, and five-year survival rates range from 80 percent for stage IB disease to 30 percent for stage III disease [1,2].

The approach to women with locally advanced cervical cancer is reviewed here. Because the predominant histology of cervical cancer is squamous cell carcinoma, specific issues related to other histologies and other topics relevant to cervical cancer in general are covered elsewhere.

(See "Management of early-stage cervical cancer".)

(See "Invasive cervical cancer: Staging and evaluation of lymph nodes".)

(See "Small cell neuroendocrine carcinoma of the cervix".)

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Literature review current through: Dec 2017. | This topic last updated: Aug 21, 2017.
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