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Management of keloid and hypertrophic scars following burn injuries

Gerd G Gauglitz, MMS, MD
Section Editor
Marc G Jeschke, MD, PhD
Deputy Editor
Kathryn A Collins, MD, PhD, FACS


Keloids and hypertrophic scars (HTS) are an aberration of physiologic wound healing characterized by greater and more sustained extracellular matrix (ECM) deposition. They may also develop following any insult to the dermis. Keloids, including those that develop from burn wounds, represent benign skin lesions. Genetic susceptibility, specific anatomic locations, prolonged inflammation, and delayed epithelialization significantly contribute to excessive scar formation [1]. Keloids affect the patient’s quality of life, both physically and psychologically, causing pain, pruritus, and contractures [2,3].

This topic will discuss the goals of therapy, diagnostic evaluation, and management of keloids and HTS that occur as a result of a burn. Pathogenesis of keloids, reconstructive principles for burn patients, and management of the burn patient are reviewed as separate topics and include:

(See "Keloids and hypertrophic scars".)

(See "Principles of burn reconstruction: Overview of surgical procedures".)

(See "Principles of burn reconstruction: Face, scalp, and neck".)

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Literature review current through: Oct 2017. | This topic last updated: Feb 09, 2016.
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