Management of infection in exacerbations of chronic obstructive pulmonary disease
- John G Bartlett, MD
John G Bartlett, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — HIV; Pulmonary Infections
- Professor Emeritus
- Johns Hopkins University School of Medicine
- Sanjay Sethi, MD
Sanjay Sethi, MD
- Professor of Medicine, Division Chief, Pulmonary/Critical Care/Sleep Medicine
- University at Buffalo, State University of New York
- Section Editor
- Daniel J Sexton, MD
Daniel J Sexton, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Bacterial Infections
- Professor of Medicine
- Duke University Medical Center
- Deputy Editors
- Anna R Thorner, MD
Anna R Thorner, MD
- Deputy Editor — Infectious Diseases
- Assistant Professor of Medicine, Part-time
- Harvard Medical School
- Helen Hollingsworth, MD
Helen Hollingsworth, MD
- Deputy Editor — Pulmonary, Critical Care, and Sleep Medicine
- Associate Professor of Medicine
- Boston University School of Medicine
The Global Initiative for Chronic Obstructive Lung Disease, a report produced by the National Heart, Lung, and Blood Institute and the World Health Organization, defines an exacerbation of chronic obstructive pulmonary disease (COPD) as an acute increase in symptoms beyond normal day-to-day variation . This generally includes one or more of the following cardinal symptoms:
●Cough increases in frequency and severity
●Sputum production increases in volume and/or changes character
Qualitative research has highlighted the prevalence of chest tightness and discomfort, sleep disturbance, anxiety, and fatigue during exacerbations .
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