Medline ® Abstract for Reference 36
of 'Management of gastrointestinal lymphomas'
Minimal residual low-grade gastric MALT-type lymphoma after eradication of Helicobacter pylori.
Fischbach W, Goebeler-Kolve M, Starostik P, Greiner A, Müller-Hermelink HK
Helicobacter pylori eradication is the initial treatment of choice in localised low-grade gastric MALT (mucosa-associated lymphoid-tissue)-type lymphoma. We describe the natural course of seven patients who refused further oncological treatment for persistent lymphoma after successful eradication of H pylori. Despite persistent clonality, neither lymphoma progression nor high-grade transformation arose during a mean observation period of 34 (range 22-44) months. In view of the favourable course of these patients, a watch-and-wait strategy could be a valid approach to management of this disease.
Department of Internal Medicine II, Klinikum Aschaffenburg, 63739 Aschaffenburg, Germany. firstname.lastname@example.org