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Medline ® Abstract for Reference 36

of 'Management of gastrointestinal lymphomas'

Minimal residual low-grade gastric MALT-type lymphoma after eradication of Helicobacter pylori.
Fischbach W, Goebeler-Kolve M, Starostik P, Greiner A, Müller-Hermelink HK
Lancet. 2002;360(9332):547.
Helicobacter pylori eradication is the initial treatment of choice in localised low-grade gastric MALT (mucosa-associated lymphoid-tissue)-type lymphoma. We describe the natural course of seven patients who refused further oncological treatment for persistent lymphoma after successful eradication of H pylori. Despite persistent clonality, neither lymphoma progression nor high-grade transformation arose during a mean observation period of 34 (range 22-44) months. In view of the favourable course of these patients, a watch-and-wait strategy could be a valid approach to management of this disease.
Department of Internal Medicine II, Klinikum Aschaffenburg, 63739 Aschaffenburg, Germany. wolfgang.fischback@klinikum-aschaffenbug.de