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Management of endometrial hyperplasia

Robert L Giuntoli, II, MD
Howard A Zacur, MD, PhD
Section Editor
Barbara Goff, MD
Deputy Editor
Sandy J Falk, MD, FACOG


Endometrial hyperplasia is characterized by a proliferation of endometrial glands (the lining of the uterine cavity) that may progress to or coexist with endometrial cancer   The majority of cases of endometrial hyperplasia result from chronic exposure of the endometrium to estrogen unopposed by a progestin. Obese postmenopausal women and premenopausal patients with polycystic ovarian syndrome represent two high-risk groups. The majority of women present with abnormal uterine bleeding.

Related topics can be found separately:

Classifications, clinical manifestations, and diagnosis of endometrial hyperplasia (See "Classification and diagnosis of endometrial hyperplasia".)

Other etiologies of abnormal uterine bleeding (See "Approach to abnormal uterine bleeding in nonpregnant reproductive-age women" and "Postmenopausal uterine bleeding".)

Endometrial cancer (See "Endometrial carcinoma: Epidemiology and risk factors".)

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Literature review current through: Sep 2017. | This topic last updated: Oct 07, 2014.
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