Barrett's esophagus is the condition in which a metaplastic columnar epithelium that predisposes to cancer development replaces the stratified squamous epithelium that normally lines the distal esophagus . The metaplastic epithelium is acquired as a consequence of chronic gastroesophageal reflux disease (GERD).
The management of patients with Barrett's esophagus involves three major components:
●Treatment of the associated GERD
●Endoscopic surveillance to detect dysplasia
●Treatment of dysplasia