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Medline ® Abstract for Reference 37

of 'Management and prognosis of tricuspid regurgitation'

Clinical outcome after isolated tricuspid valve replacement: 20-year experience.
Do QB, Pellerin M, Carrier M, Cartier R, Hébert Y, PagéP, Perrault LP, Pelletier LC
Can J Cardiol. 2000;16(4):489.
OBJECTIVE: To examine the early and late results of isolated tricuspid valve replacement (TVR).
DESIGN AND SETTING: All isolated TVRs performed at the Montreal Heart Institute, Montreal, Quebec between January 1978 and January 1998 were retrospectively reviewed. Follow-up data on patients were obtained through the valve clinic.
PARTICIPANTS: From a total of 79 TVR and 375 tricuspid annuloplasties performed during the study period, 29 patients who underwent 32 isolated TVRs (six mechanical valves and 26 bioprostheses) were included. Patient age ranged from 25 to 70 years (mean 48), and 62% were female. Twenty-seven patients (84%) were in New York Heart Association (NYHA) functional classes III and IV. Previous valve surgery had been performed in 22 patients (69%) among whom nine had undergone TVR.
RESULTS: Postoperatively, a permanent pacemaker was implanted in nine patients (28%), and reoperation because of bleeding was required in two patients. Mean follow-up was 67.7 months (93% complete). Serial echocardiography showed prosthesis dysfunction in three patients, requiring two valve re-replacements at 12.8 and 7.7 years after initial surgery. All patients, except three, showed an improvement of their NYHA class. Six patients (19%) died in hospital and seven patients died during late follow-up at a mean of 38.1 months after surgery, including one valve-related death (mechanical valve thrombosis). The actuarial survival rate of all patients was 63% after five years and 47% after 10 years.
CONCLUSION: Isolated TVR remains a high risk procedure. Most survivors, however, should expect a better quality of life by the improvement in their NYHA class.
Montreal Heart Institute, Montreal, Canada.