Management and prognosis of tricuspid regurgitation


Tricuspid regurgitation (TR) is a relatively common abnormality. Since this lesion is frequently asymptomatic and may not be detected on physical examination, it is often diagnosed solely by echocardiography. This topic will review the prognosis and management of tricuspid regurgitation.

Etiology, clinical features, and evaluation of tricuspid regurgitation are discussed separately. (See "Etiology, clinical features, and evaluation of tricuspid regurgitation".)


Most cases of TR in adults are functional, with a minority of cases due to primary acquired or congenital valve disease. Functional TR is commonly associated with left-sided heart disease, particularly mitral valve disease and/or left heart failure. (See "Etiology, clinical features, and evaluation of tricuspid regurgitation", section on 'Etiology'.) Acquired cause of TR in adults includes endocarditis, traumatic flail leaflet, and impingement of pacer leads on tricuspid valve closure.

Most cases of TR due to valve disease in adolescents and young adults are congenital, with Ebstein's anomaly being most common [1]. (See "Ebstein's anomaly of the tricuspid valve".)

While the clinical setting (particularly concomitant cardiovascular disease) influences survival in patients with TR, severe TR is an independent predictor of mortality as illustrated by the following studies:


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Literature review current through: Jun 2014. | This topic last updated: Aug 14, 2013.
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