A case of hippocampal laminar necrosis following complex partial status epilepticus

Acta Neurol Scand. 2007 Jun;115(6):425-8. doi: 10.1111/j.1600-0404.2006.00784.x.

Abstract

Cortical laminar necrosis (CLN) is a metabolic injury pattern usually observed after cerebral hypoxia, hypoglycemia, or ischemia. We report serial magnetic resonance imaging findings in a patient with complex partial status epilepticus (SE) developing a band-like, T1-hyperintense lesion consistent with CLN along the surface of the left hippocampus without concurrent other causes of CLN. This observation suggests a direct pathogenetic link between SE and CLN involving combined damage to neurons and glia.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Brain Damage, Chronic / etiology
  • Brain Damage, Chronic / pathology*
  • Brain Damage, Chronic / physiopathology
  • Epilepsy / complications
  • Epilepsy / pathology*
  • Epilepsy / physiopathology
  • Gliosis / etiology
  • Gliosis / pathology
  • Gliosis / physiopathology
  • Hippocampus / pathology*
  • Hippocampus / physiopathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Necrosis / etiology
  • Necrosis / pathology
  • Necrosis / physiopathology
  • Nerve Degeneration / etiology
  • Nerve Degeneration / pathology
  • Nerve Degeneration / physiopathology
  • Status Epilepticus / complications
  • Status Epilepticus / pathology*
  • Status Epilepticus / physiopathology