Official reprint from UpToDate®
www.uptodate.com ©2017 UpToDate, Inc. and/or its affiliates. All Rights Reserved.

Medline ® Abstract for Reference 35

of 'Iron requirements and iron deficiency in adolescents'

Dietary iron intake and iron status in adolescents.
Samuelson G, Bratteby LE, Berggren K, Elverby JE, Kempe B
Acta Paediatr. 1996;85(9):1033.
The aim of this study was to evaluate the dietary iron intake of 15-year-old adolescents from two different regions of Sweden, in relation to their iron status. The study comprised 185 boys and 209 girls, randomly selected from the official population register. The iron intake was calculated from a 7-day record, and varied between 7 and 35 and 6 and 27 mg per day for boys and girls, respectively. The daily median intakes in boys and girls were 18.7 and 14.2 mg, respectively. S-ferritin, s-iron, and s-transferrin saturation, measured in all the subjects, did not differ significantly between the two regions. However, the mean serum ferritin concentration was significantly higher in the boys (36.4 micrograms l-1) than in the girls (29.4 micrograms l-1) (p<0.001). Low s-ferritin levels, defined as s-ferritin<12 micrograms l-1 were found in seven boys (3.7%) and in 29 girls (13.9%). None of the adolescents had iron deficiency anaemia, defined as Hb<110 gl-1 in combination with s-ferritin<12 micrograms l-1. Regression and correlation analyses did not show any significant correlation between dietary iron intake and s-ferritin, or between s-ferritin and haemoglobin (Hb), MCH and MCHC. A significant correlation was found, however, between s-ferritin and transferrin saturation (p<0.005) in both sexes. When the adolescents who still had s-ferritin<12 micrograms l-1 at a second blood examination were given a 6 weeks trial with oral iron therapy, all of them showed an increase both in s-ferritin and in blood Hb. The 95% confidence intervals of s-ferritin for 15-year-old Swedish boys and girls were defined as 11-90 and 7-85 micrograms l-1, respectively.
Department of Clinical Physiology, University of Uppsala, Sweden.