Propionibacteria are part of the normal flora of human skin and mucosal surfaces. Occasionally, they cause clinically significant infections, particularly in the setting of shoulder surgery, orthopedic hardware, endovascular devices, and cerebrospinal shunts. It can be difficult to determine whether positive culture results for Propionibacteria reflect contamination or true infection.
Infections with Propionibacterium species can be classified into three categories:
●Acne in teenagers and young adults (when caused by P. acnes)
●Surgical wound infections
●Invasive deep seated infections, usually in the setting of implantable devices (eg, pacemakers, shunts, etc)