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Intravenous immune globulin: Adverse effects

Elena E Perez, MD, PhD
Arthur J Silvergleid, MD
Section Editor
E Richard Stiehm, MD
Deputy Editors
Jennifer S Tirnauer, MD
Anna M Feldweg, MD


Intravenous immune globulin (IVIG) is a product prepared from human plasma used to treat a variety of immunodeficiency and autoimmune conditions.

This topic review discusses potential adverse reactions to IVIG, along with strategies to minimize these reactions and our approach to treatment.

Separate topic reviews discuss the clinical uses of IVIG and products for subcutaneous and intramuscular administration:

Overview of uses and available intravenous products – (See "Overview of intravenous immune globulin (IVIG) therapy".)

Overview of uses and available subcutaneous and intramuscular products – (See "Subcutaneous and intramuscular immune globulin therapy".)

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Literature review current through: Oct 2017. | This topic last updated: Jun 19, 2017.
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