- Karin Leder, MBBS, FRACP, PhD, MPH, DTMH
Karin Leder, MBBS, FRACP, PhD, MPH, DTMH
- Section Editor — Travel Medicine
- Head of Infectious Diseases Unit
- Monash University, Australia
- Peter F Weller, MD, FACP
Peter F Weller, MD, FACP
- Editor-in-Chief — Infectious Diseases
- Section Editor — Tropical Medicine
- William Bosworth Castle Professor of Medicine
- Harvard Medical School
- Professor of Immunology and Infectious Diseases
- Harvard T. H. Chan School of Public Health
Tapeworms (cestodes) are flat, hermaphroditic worms that can live as parasites in the human gastrointestinal tract. Some of these organisms are primarily human pathogens, while others have animals as their natural hosts but can also cause human infection.
Taeniasis, Diphyllobothriasis, Hymenolepiasis, and Dipylidiasis will be reviewed here. Ingestion of the eggs of Taenia solium causes cysticercosis, a tapeworm infection that is discussed separately. (See "Epidemiology, transmission and prevention of cysticercosis" and "Clinical manifestations and diagnosis of cysticercosis" and "Treatment of cysticercosis".)
Adult tapeworms consist of a head, neck, and segmented body. The head (also known as a scolex) is equipped with suckers, hooks, or grooves (depending upon the species); the worm uses these to attach itself to the intestine of the host.
Each segment (known as a proglottid) has a complete set of reproductive organs. Depending on the species, the adult worm may have hundreds or thousands of proglottids. In some species (such as Taenia), the distal segments can separate from the rest of the body and the proglottids (or the eggs they contain) are passed in the stool. In other species (such as Hymenolepis), proglottids degenerate within the host so only eggs are found in the stool.
Tapeworms are covered with a tegument through which they absorb nutrients and secrete waste. Different species of tapeworms can be differentiated by morphologic characteristics of the scolex, proglottids, and eggs .
- Schantz PM. Tapeworms (cestodiasis). Gastroenterol Clin North Am 1996; 25:637.
- Flisser A, Viniegra AE, Aguilar-Vega L, et al. Portrait of human tapeworms. J Parasitol 2004; 90:914.
- Eom KS. What is Asian Taenia? Parasitol Int 2006; 55 Suppl:S137.
- Hoberg EP. Phylogeny of Taenia: Species definitions and origins of human parasites. Parasitol Int 2006; 55 Suppl:S23.
- Botero D, Tanowitz HB, Weiss LM, Wittner M. Taeniasis and cysticercosis. Infect Dis Clin North Am 1993; 7:683.
- Schantz PM, Moore AC, Muñoz JL, et al. Neurocysticercosis in an Orthodox Jewish community in New York City. N Engl J Med 1992; 327:692.
- Craig P, Ito A. Intestinal cestodes. Curr Opin Infect Dis 2007; 20:524.
- Flisser A, Plancarte A, Correa D, et al. New approaches in the diagnosis of Taenia solium cysticercosis and taeniasis. Ann Parasitol Hum Comp 1990; 65 Suppl 1:95.
- Allan JC, Avila G, Garcia Noval J, et al. Immunodiagnosis of taeniasis by coproantigen detection. Parasitology 1990; 101 Pt 3:473.
- Maass M, Delgado E, Knobloch J. Detection of Taenia solium antigens in merthiolate-form preserved stool samples. Trop Med Parasitol 1991; 42:112.
- Chapman A, Vallejo V, Mossie KG, et al. Isolation and characterization of species-specific DNA probes from Taenia solium and Taenia saginata and their use in an egg detection assay. J Clin Microbiol 1995; 33:1283.
- Allan JC, Craig PS. Coproantigens in taeniasis and echinococcosis. Parasitol Int 2006; 55 Suppl:S75.
- Allan JC, Mencos F, Garcia-Noval J, et al. Dipstick dot ELISA for the detection of Taenia coproantigens in humans. Parasitology 1993; 107 ( Pt 1):79.
- Deplazes P, Eckert J, Pawlowski ZS, et al. An enzyme-linked immunosorbent assay for diagnostic detection of Taenia saginata copro-antigens in humans. Trans R Soc Trop Med Hyg 1991; 85:391.
- Cabello FC. Salmon aquaculture and transmission of the fish tapeworm. Emerg Infect Dis 2007; 13:169.
- Nakaji K, Suzumura S, Nakae Y, et al. Effects in the control of edema of the papilla of Vater by epinephrine saline irrigation after endoscopic retrograde cholangiopancreatography in an endoscopy center in Japan, 2003 to 2007: exploratory retrospective analysis to evaluate the characteristics of eligible patients with a focus on serum amylase levels. Intern Med 2009; 48:945.
- Flores EC, Plumb SC, McNeese MC. Intestinal parasitosis in an urban pediatric clinic population. Am J Dis Child 1983; 137:754.
- Groll E. Praziquantel for cestode infections in man. Acta Trop 1980; 37:293.
- Drugs for parasitic infections. Med Lett Drugs Ther 2010; 8:e20.
- Pawłowski ZS. Efficacy of low doses of praziquantel in taeniasis. Acta Trop 1990; 48:83.
- Brindley PJ, Sher A. Immunological involvement in the efficacy of praziquantel. Exp Parasitol 1990; 71:245.
- Frayha GJ, Smyth JD, Gobert JG, Savel J. The mechanisms of action of antiprotozoal and anthelmintic drugs in man. Gen Pharmacol 1997; 28:273.
- Juan JO, Lopez Chegne N, Gargala G, Favennec L. Comparative clinical studies of nitazoxanide, albendazole and praziquantel in the treatment of ascariasis, trichuriasis and hymenolepiasis in children from Peru. Trans R Soc Trop Med Hyg 2002; 96:193.
- Chero JC, Saito M, Bustos JA, et al. Hymenolepis nana infection: symptoms and response to nitazoxanide in field conditions. Trans R Soc Trop Med Hyg 2007; 101:203.