Medline ® Abstract for Reference 63
of 'Interferon-gamma release assays for diagnosis of latent tuberculosis infection'
63
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Quantiferon-Gold Tuberculosis Test Cannot Detect Latent Tuberculosis in Patients With Leprosy.
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Rendini T, Levis W
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Clin Infect Dis. 2015 Nov;61(9):1439-40. Epub 2015 Jul 24.
Five of 10 paucibacillary leprosy patients were Quantiferon Gold (Q-G) positive with negative chest X-rays. Forty multibacillary leprosy patients were negative. Reports have shown 100% cross-reactivity of ESAT6 and CFP10 between Mycobacterium leprae and Mycobacterium tuberculosis. The Q-G test cannot detect latent tuberculosis in patients with leprosy.
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Bellevue Hospital Center, New York Hansen's Disease Program, New York.
PMID