Medline ® Abstract for Reference 55
of 'Interferon-gamma release assays for diagnosis of latent tuberculosis infection'
55
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Preanalytical delay reduces sensitivity of QuantiFERON-TB gold in-tube assay for detection of latent tuberculosis infection.
AU
Doberne D, Gaur RL, Banaei N
SO
J Clin Microbiol. 2011 Aug;49(8):3061-4. Epub 2011 Jun 22.
The effects of incubation delays on the accuracy of the QuantiFERON-TB gold in-tube assay (QFT-GIT) were measured. Compared to immediate incubation, 6- and 12-hour delays resulted in positive-to-negative reversion rates of 19% (5/26) and 22% (5/23), respectively. These findings underscore the need for standardizing QFT-GIT preanalytical practices.
AD
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PMID