Medline ® Abstract for Reference 50
of 'Infectious complications of intravesical BCG immunotherapy'
50
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Multiple mycotic aneurysms due to Mycobacterium bovis after intravesical bacillus Calmette-Guérin therapy.
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Coscas R, Arlet JB, Belhomme D, Fabiani JN, Pouchot J
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J Vasc Surg. 2009;50(5):1185. Epub 2009 Aug 5.
Mycotic aneurysms are exceptional complications after intravesical instillations of bacillus Calmette-Guérin (BCG) for bladder carcinoma. We report a patient who underwent an emergency operation for a ruptured carotid aneurysm 16 months after BCG therapy. Postoperative investigations discovered multiple other synchronous aneurysms. Culture of an abscess surrounding the right carotid artery identified Mycobacterium bovis var BCG. The patient improved clinically with antituberculous agents prescribed for 9 months but died from recurrence of bladder carcinoma 16 months later. A mycotic origin should be evoked when an aneurysm is discovered after BCG therapy. Microbiologic investigation of the artery wall is diagnostic.
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Department of Cardiovascular Surgery, Facultéde Médecine Paris Descartes et Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
PMID