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Infections and antimicrobial resistance in the intensive care unit: Epidemiology and prevention

Authors
Dror Marchaim, MD
Keith Kaye, MD, MPH
Section Editor
Anthony Harris, MD, MPH
Deputy Editor
Elinor L Baron, MD, DTMH

INTRODUCTION

Although intensive care units (ICUs) account for fewer than 10 percent of total beds in most hospitals, more than 20 percent of all nosocomial infections are acquired in ICUs [1]. ICU-acquired infections account for substantial morbidity, mortality, and expense. Infections and sepsis are the leading cause of death in noncardiac ICUs and account for 40 percent of all ICU expenditures [2].

The epidemiology of nosocomial ICU infections and antimicrobial resistance in ICUs will be discussed here. The most important nosocomial infections in the ICU, namely catheter-related bloodstream infections (CRBSIs), ventilator-associated pneumonia (VAP), and catheter-associated urinary tract infections (CAUTIs), will be discussed briefly here and in more detail separately:

(See "Catheter-associated urinary tract infection in adults" and "Complications of urinary bladder catheters and preventive strategies".)

(See "Epidemiology, pathogenesis, microbiology, and diagnosis of hospital-acquired and ventilator-associated pneumonia in adults" and "Treatment of hospital-acquired and ventilator-associated pneumonia in adults" and "Risk factors and prevention of hospital-acquired and ventilator-associated pneumonia in adults".)

(See "Epidemiology, pathogenesis, and microbiology of intravascular catheter infections" and "Treatment of intravascular catheter-related infections" and "Prevention of intravascular catheter-related infections".)

                    

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Literature review current through: Nov 2016. | This topic last updated: Fri Aug 26 00:00:00 GMT+00:00 2016.
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