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Immune thrombocytopenia (ITP) in adults: Second- and third-line therapies

INTRODUCTION

Therapy for immune thrombocytopenia (ITP) differs for different patients: some do not require any treatment; others have a spontaneous remission or respond to first-line therapy with glucocorticoids and/or intravenous immune globulin (IVIG); and others continue to have severe thrombocytopenia and/or bleeding, necessitating additional therapy.

Here we discuss our approach to management of adults with ITP who require additional therapy beyond glucocorticoids and IVIG (ie, second- and third-line therapy). The clinical manifestations, diagnosis, and initial treatment of adults and children presenting with ITP are discussed in detail separately.

(See "Immune thrombocytopenia (ITP) in adults: Clinical manifestations and diagnosis".)

(See "Immune thrombocytopenia (ITP) in adults: Initial treatment and prognosis".)

(See "Immune thrombocytopenia (ITP) in children: Initial management".)

                          

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Literature review current through: Sep 2014. | This topic last updated: Aug 5, 2014.
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