Medline ® Abstract for Reference 84
of 'Immune reconstitution inflammatory syndrome'
84
TI
Extensive retinal neovascularization as a late finding in human immunodeficiency virus-infected patients with immune recovery uveitis.
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Wright ME, Suzman DL, Csaky KG, Masur H, Polis MA, Robinson MR
SO
Clin Infect Dis. 2003;36(8):1063.
Sixteen human immunodeficiency virus (HIV)-infected patients with inactive cytomegalovirus (CMV) retinitis who had discontinued systemic anti-CMV therapy while receiving highly active antiretroviral therapy (HAART) were prospectively observed. Fifteen patients developed immune recovery uveitis (IRU); 3 of the patients developed extensive retinal neovascularization, 1 of whom required vitrectomy for recurrent vitreous hemorrhages. These late complications indicate a need for continued ophthalmologic follow-up of HIV-infected patients who have a history of CMV retinitis, even for individuals who have not required anti-CMV therapy for>4 years.
AD
National Institute of Allergy and Infectious Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland 20892, USA.
PMID