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Medline ® Abstract for Reference 83

of 'Immune reconstitution inflammatory syndrome'

83
TI
HIV combination therapy: immune restitution causing cryptococcal lymphadenitis dramatically improved by anti-inflammatory therapy.
AU
Blanche P, Gombert B, Ginsburg C, Passeron A, Stubei I, Rigolet A, Salmon D, Sicard D
SO
Scand J Infect Dis. 1998;30(6):615.
 
Two patients with AIDS developed microscopically verified focal cryptococcal lymphadenitis while treated with highly active anti-retroviral therapy for 8 and 15 months. Both were treated with fluconazole as a secondary prophylaxis for prior cryptococcal meningitis. Cryptococcus neoformans did not grow. Amphotericin was ineffective. Anti-inflammatory drugs had a dramatic effect.
AD
Service de Médecine Interne 2, Hôpital Cochin, UniversitéRenéDescartes, Paris, France.
PMID