Medline ® Abstract for Reference 80
of 'Immune reconstitution inflammatory syndrome'
80
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The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy.
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Shelburne SA 3rd, Darcourt J, White AC Jr, Greenberg SB, Hamill RJ, Atmar RL, Visnegarwala F
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Clin Infect Dis. 2005;40(7):1049.
This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis.
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Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas, USA. samuels@bcm.tmc.edu
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