Medline ® Abstract for Reference 103
of 'Immune reconstitution inflammatory syndrome'
103
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Immune reconstitution hepatitis in HIV and hepatitis B coinfection, despite lamivudine therapy as part of HAART.
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Drake A, Mijch A, Sasadeusz J
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Clin Infect Dis. 2004;39(1):129. Epub 2004 Jun 1.
Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) coinfection occurs commonly. The introduction of antiretroviral therapy can result in immune reconstitution hepatitis. We describe 2 coinfected patients who developed clinical flares of HBV disease, despite the inclusion of lamivudine, a drug with anti-HBV activity, in their HAART regimens. Potential strategies to manage individuals with HBV/HIV coinfection are discussed.
AD
The Alfred Hospital, Melbourne, Australia. DRAKEA@svhm.org.au
PMID