Medline ® Abstract for Reference 23
of 'Immediate hypersensitivity reactions to radiocontrast media: Clinical manifestations, diagnosis, and treatment'
Prekallikrein-Kallikrein conversion rate as a predictor of contrast material catastrophies.
Lasser EC, Lang JH, Lyon SG, Hamblin AE, Howard MM
An in vitro is described that attempts to detect patients with a potential for adverse systemic reactions to contrast material. This test involves measuring the rate of conversion of prekallikrein to kallikrein under certain standard conditions. In a preliminary retrospective study, the test could be used to identify such patients with a sensitivity of 88%, a specificity of 82%, and a predictive value of 79%.