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Henoch-Schönlein purpura (IgA vasculitis): Clinical manifestations and diagnosis

INTRODUCTION

Henoch-Schönlein purpura (HSP), also called IgA vasculitis (IgAV) [1], is the most common form of systemic vasculitis in children. Ninety percent of cases occur in the pediatric age group. In contrast to many other forms of systemic vasculitis, HSP (IgAV) is self limited in the great majority of cases. The disease is characterized by a tetrad of clinical manifestations:

Palpable purpura in patients with neither thrombocytopenia nor coagulopathy

Arthritis/arthralgia

Abdominal pain

Renal disease

                               

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Literature review current through: Nov 2014. | This topic last updated: Jun 2, 2014.
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