Osteomyelitis refers to an infection of bone. It is usually bacterial in origin. Microorganisms can be introduced into bone in three ways:
●Direct inoculation (usually traumatic, but also surgical)
●Local invasion from a contiguous infection
In children, acute osteomyelitis is generally hematogenous in origin. Unique anatomic characteristics of the growing skeleton also affect the site of infection, pathogenesis, and clinical features of the disease on account of hematogenous spread.