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Hematogenous osteomyelitis in children: Epidemiology, pathogenesis, and microbiology

INTRODUCTION

Osteomyelitis refers to an infection of bone. It is usually bacterial in origin. Microorganisms can be introduced into bone in three ways:

Hematogenous delivery

Direct inoculation (usually traumatic, but also surgical)

Local invasion from a contiguous infection

In children, acute osteomyelitis is generally hematogenous in origin. Unique anatomic characteristics of the growing skeleton also affect the site of infection, pathogenesis, and clinical features of the disease on account of hematogenous spread.

                    

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Literature review current through: Jul 2014. | This topic last updated: Jan 10, 2014.
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